Anti-Cleaved-ADAM12-Glu208 antibody (207-208) (STJA0005817) STJA0005817 上海玉博生物科技有限公司

Anti-Cleaved-ADAM12-Glu208 antibody (207-208) (STJA0005817)

简单介绍

Anti-Cleaved-ADAM12-Glu208 antibody (207-208) (STJA0005817)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cleaved-Disintegrin and metalloproteinase domain-containing protein 12-Glu208 (207-208) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:1000-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ADAM12
Gene ID:	8038
Uniprot ID:	ADA12_HUMAN
Immunogen Region:	207-208
Specificity:	This antibody detects endogenous levels of Human, Mouse ADAM 12 (Cleaved-Glu208, protein was cleaved amino acid sequence between 207-208)
Immunogen:	Synthesized peptide derived from human ADAM 12 (Cleaved-Glu208)

Tissue Specificity	Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas.
Post Translational Modifications	The precursor is cleaved by a furin endopeptidase.
Function	Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors.
Protein Name	Disintegrin And Metalloproteinase Domain-Containing Protein 12 Adam 12 Meltrin-Alpha
Database Links	Reactome: R-HSA-177929 Reactome: R-HSA-8941237
Cellular Localisation	Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Isoform 2: Secreted Isoform 3: Secreted Isoform 4: Secreted
Alternative Antibody Names	Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 12 antibody Anti-Adam 12 antibody Anti-Meltrin-Alpha antibody Anti-ADAM12 antibody Anti-MLTN antibody Anti-UNQ346 antibody Anti-PRO545 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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