Anti-Cleaved-CASP2-T325 antibody (276-325 aa) (STJ90024) STJ90024 上海玉博生物科技有限公司

Anti-Cleaved-CASP2-T325 antibody (276-325 aa) (STJ90024)

简单介绍

Anti-Cleaved-CASP2-T325 antibody (276-325 aa) (STJ90024)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cleaved-Caspase-2-T325 (276-325 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 ELISA 1:10000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CASP2
Gene ID:	835
Uniprot ID:	CASP2_HUMAN
Immunogen Region:	276-325 aa
Specificity:	Cleaved-Caspase-2 p18 (T325) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-2 p18 protein resulting from cleavage adjacent to T325.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human Caspase 2 p18 C-ternal at the amino acid range 276-325

Post Translational Modifications	The mature protease can process its own propeptide, but not that of other caspases.
Function	Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress.
Protein Name	Caspase-2 Casp-2 Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 2 Nedd-2 Protease Ich-1 Cleaved Into - Caspase-2 Subunit P18 - Caspase-2 Subunit P13 - Caspase-2 Subunit P12
Database Links	Reactome: R-HSA-168638 Reactome: R-HSA-205025 Reactome: R-HSA-6803207
Alternative Antibody Names	Anti-Caspase-2 antibody Anti-Casp-2 antibody Anti-Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 2 antibody Anti-Nedd-2 antibody Anti-Protease Ich-1 Cleaved Into - Caspase-2 Subunit P18 - Caspase-2 Subunit P13 - Caspase-2 Subunit P12 antibody Anti-CASP2 antibody Anti-ICH1 antibody Anti-NEDD2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

产品目录