Anti-Cleaved-COL3A1-G1221 antibody (1172-1221 aa) (STJ90049) STJ90049 上海玉博生物科技有限公司

Anti-Cleaved-COL3A1-G1221 antibody (1172-1221 aa) (STJ90049)

简单介绍

Anti-Cleaved-COL3A1-G1221 antibody (1172-1221 aa) (STJ90049)

产品描述

Host:	Rabbit
Applications:	ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cleaved-Collagen alpha-1III chain-G1221 (1172-1221 aa) is suitable for use in ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	ELISA 1:10000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	COL3A1
Gene ID:	1281
Uniprot ID:	CO3A1_HUMAN
Immunogen Region:	1172-1221 aa
Specificity:	Cleaved-COL3A1 (G1221) Polyclonal Antibody detects endogenous levels of fragment of activated COL3A1 protein resulting from cleavage adjacent to G1221.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human Collagen III alpha1 at the amino acid range 1172-1221

Function	Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
Protein Name	Collagen Alpha-1(Iii Chain
Database Links	Reactome: R-HSA-1442490 Reactome: R-HSA-1474244 Reactome: R-HSA-1650814 Reactome: R-HSA-186797 Reactome: R-HSA-198933 Reactome: R-HSA-2022090 Reactome: R-HSA-216083 Reactome: R-HSA-3000170 Reactome: R-HSA-3000171 Reactome: R-HSA-3000178 Reactome: R-HSA-3000480 Reactome: R-HSA-419037 Reactome: R-HSA-8874081 Reactome: R-HSA-8948216
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Collagen Alpha-1(Iii Chain antibody Anti-COL3A1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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