Anti-Cleaved-CTSC-Asp395, Light Chain antibody (394-395) (STJA0005854) STJA0005854 上海玉博生物科技有限公司

Anti-Cleaved-CTSC-Asp395, Light Chain antibody (394-395) (STJA0005854)

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产品名称：Anti-Cleaved-CTSC-Asp395, Light Chain antibody (394-395) (STJA0005854)
产品型号：STJA0005854
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-Cleaved-CTSC-Asp395, Light Chain antibody (394-395) (STJA0005854)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cleaved-Dipeptidyl peptidase 1-Asp395, Light Chain (394-395) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:1000-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CTSC
Gene ID:	1075
Uniprot ID:	CATC_HUMAN
Immunogen Region:	394-395
Specificity:	This antibody detects endogenous levels of Human Dipeptidyl-peptidase 3 (light chain, Cleaved-Asp395, protein was cleaved amino acid sequence between 394-395 )
Immunogen:	Synthesized peptide derived from human Dipeptidyl-peptidase 1 (light chain, Cleaved-Asp395)

Tissue Specificity	Ubiquitous. Highly expressed in lung, kidney and placenta. Detected at intermediate levels in colon, small intestine, spleen and pancreas.
Post Translational Modifications	N-glycosylated. While glycosylation at Asn-53, Asn-119 and Asn-276 is mediated by STT3A-containing complexes, glycosylation at Asn-29 is mediated STT3B-containing complexes. In approximately 50% of the complexes the exclusion domain is cleaved at position 58 or 61. The two parts of the exclusion domain are held together by a disulfide bond.
Function	Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B.
Protein Name	Dipeptidyl Peptidase 1 Cathepsin C Cathepsin J Dipeptidyl Peptidase I Dpp-I Dppi Dipeptidyl Transferase Cleaved Into - Dipeptidyl Peptidase 1 Exclusion Domain Chain Dipeptidyl Peptidase I Exclusion Domain Chain - Dipeptidyl Peptidase 1 Heavy Chain Dipeptidyl Peptidase I Heavy Chain - Dipeptidyl Peptidase 1 Light Chain Dipeptidyl Peptidase I Light Chain
Database Links	Reactome: R-HSA-204005 Reactome: R-HSA-2132295 Reactome: R-HSA-5694530 Reactome: R-HSA-6798695
Cellular Localisation	Lysosome
Alternative Antibody Names	Anti-Dipeptidyl Peptidase 1 antibody Anti-Cathepsin C antibody Anti-Cathepsin J antibody Anti-Dipeptidyl Peptidase I antibody Anti-Dpp-I antibody Anti-Dppi antibody Anti-Dipeptidyl Transferase Cleaved Into - Dipeptidyl Peptidase 1 Exclusion Domain Chain antibody Anti-Dipeptidyl Peptidase I Exclusion Domain Chain - Dipeptidyl Peptidase 1 Heavy Chain antibody Anti-Dipeptidyl Peptidase I Heavy Chain - Dipeptidyl Peptidase 1 Light Chain antibody Anti-Dipeptidyl Peptidase I Light Chain antibody Anti-CTSC antibody Anti-CPPI antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-Cleaved-CTSC-Asp395, Light Chain antibody (394-395) (STJA0005854)