Anti-Cleaved-CTSK-Ala115 antibody (114-115) (STJA0005829) STJA0005829 上海玉博生物科技有限公司

Anti-Cleaved-CTSK-Ala115 antibody (114-115) (STJA0005829)

简单介绍

Anti-Cleaved-CTSK-Ala115 antibody (114-115) (STJA0005829)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cleaved-Cathepsin K-Ala115 (114-115) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:1000-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CTSK
Gene ID:	1513
Uniprot ID:	CATK_HUMAN
Immunogen Region:	114-115
Specificity:	This antibody detects endogenous levels of Human, Mouse, Rat CATK (Cleaved-Ala115, protein was cleaved amino acid sequence between 114-115 )
Immunogen:	Synthesized peptide derived from human CATK (Cleaved-Ala115)

Tissue Specificity	Predominantly expressed in osteoclasts (bones). Expressed in thyroid epithelial cells.
Function	Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.
Protein Name	Cathepsin K Cathepsin O Cathepsin O2 Cathepsin X
Database Links	Reactome: R-HSA-1442490 Reactome: R-HSA-1474228 Reactome: R-HSA-1592389 Reactome: R-HSA-1679131 Reactome: R-HSA-2132295 Reactome: R-HSA-8939242
Cellular Localisation	Lysosome Secreted Apical Cell Membrane Peripheral Membrane Protein Extracellular Side Localizes To The Lumen Of Thyroid Follicles And To The Apical Membrane Of Thyroid Epithelial Cells
Alternative Antibody Names	Anti-Cathepsin K antibody Anti-Cathepsin O antibody Anti-Cathepsin O2 antibody Anti-Cathepsin X antibody Anti-CTSK antibody Anti-CTSO antibody Anti-CTSO2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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