Anti-Cleaved-F7-R212 antibody (171-220 aa) (STJ90080) STJ90080 上海玉博生物科技有限公司

Anti-Cleaved-F7-R212 antibody (171-220 aa) (STJ90080)

如果您对该产品感兴趣的话，可以
产品名称：Anti-Cleaved-F7-R212 antibody (171-220 aa) (STJ90080)
产品型号：STJ90080
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-Cleaved-F7-R212 antibody (171-220 aa) (STJ90080)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cleaved-Coagulation factor VII-R212 (171-220 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	F7
Gene ID:	2155
Uniprot ID:	FA7_HUMAN
Immunogen Region:	171-220 aa
Specificity:	Cleaved-Factor VII LC (R212) Polyclonal Antibody detects endogenous levels of fragment of activated Factor VII LC protein resulting from cleavage adjacent to R212.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human FA7 at the amino acid range 171-220

Post Translational Modifications	The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium. The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. O- and N-glycosylated. N-glycosylation at Asn-205 occurs cotranslationally and is mediated by STT3A-containing complexes, while glycosylation at Asn-382 is post-translational and is mediated STT3B-containing complexes before folding. O-fucosylated by POFUT1 on a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-S/T-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines. Can be either O-glucosylated or O-xylosylated at Ser-112 by POGLUT1 in vitro.
Function	Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
Protein Name	Coagulation Factor Vii Proconvertin Serum Prothrombin Conversion Accelerator Spca Eptacog Alfa Cleaved Into - Factor Vii Light Chain - Factor Vii Heavy Chain
Database Links	Reactome: R-HSA-1368108 Reactome: R-HSA-140834 Reactome: R-HSA-159740 Reactome: R-HSA-159763 Reactome: R-HSA-159782
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-Coagulation Factor Vii antibody Anti-Proconvertin antibody Anti-Serum Prothrombin Conversion Accelerator antibody Anti-Spca antibody Anti-Eptacog Alfa Cleaved Into - Factor Vii Light Chain - Factor Vii Heavy Chain antibody Anti-F7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Anti-Cleaved-F7-R212 antibody (171-220 aa) (STJ90080)