Anti-CCM2 antibody (1-300) (STJ28627) STJ28627 上海玉博生物科技有限公司

Anti-CCM2 antibody (1-300) (STJ28627)

简单介绍

Anti-CCM2 antibody (1-300) (STJ28627)

产品描述

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CCM2 (1-300) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CCM2
Gene ID:	83605
Uniprot ID:	CCM2_HUMAN
Immunogen Region:	1-300
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CCM2 (NP_113631.1).
Immunogen Sequence:	MEEEGKKGKKPGIVSPFKRV FLKGEKSRDKKAHEKVTERR PLHTVVLSLPERVEPDRLLS DYIEKEVKYLGQLTSIPGYL NPSSRTEILHFIDNAKRAHQ LPGHLTQEHDAVLSLSAYNV KLAWRDGEDIILRVPIHDIA AVSYVRDDAAHLVVLKTAQD PGISPSQSLCAESSRGLSAG SLSESAVGPVEACCLVILAA ESKVAAEELCCLLGQVFQVV YTESTIDFLDRAIFDGAST

Function	Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions. May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock.
Protein Name	Cerebral Cavernous Malformations 2 Protein Malcavernin
Cellular Localisation	Cytoplasm
Alternative Antibody Names	Anti-Cerebral Cavernous Malformations 2 Protein antibody Anti-Malcavernin antibody Anti-CCM2 antibody Anti-C7orf22 antibody Anti-PP10187 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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