Human TIMP1 (Metalloproteinase inhibitor 1) CLIA Kit (STJC0000146) STJC0000146 上海玉博生物科技有限公司

Human TIMP1 (Metalloproteinase inhibitor 1) CLIA Kit (STJC0000146)

如果您对该产品感兴趣的话，可以
产品名称：Human TIMP1 (Metalloproteinase inhibitor 1) CLIA Kit (STJC0000146)
产品型号：STJC0000146
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human TIMP1 (Metalloproteinase inhibitor 1) CLIA Kit (STJC0000146)

产品描述

Applications:	CLIA
Reactivity:	Human
Note:	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity:	18.75pg/mL
Detection Limit:	31.25~2000pg/mL
Short Description:	This human TIMP1 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.

Storage Instruction:	If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time:	3.5h
Detection:	Chemiluminescence

Gene Symbol:	TIMP1
Gene ID:	7076
Uniprot ID:	TIMP1_HUMAN
Specificity:	This kit recognizes Human TIMP-1 in samples. No significant cross-reactivity or interference between Human TIMP-1 and analogues was observed.
Sample Type:	Serum, plasma and other biological fluids

Tissue Specificity	Detected in rheumatoid synovial fluid (at protein level).
Post Translational Modifications	The activity of TIMP1 is dependent on the presence of disulfide bonds. N-glycosylated.
Function	Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro.but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
Protein Name	Metalloproteinase Inhibitor 1 Erythroid-Potentiating Activity Epa Fibroblast Collagenase Inhibitor Collagenase Inhibitor Tissue Inhibitor Of Metalloproteinases 1 Timp-1
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-1592389 Reactome: R-HSA-381426 Reactome: R-HSA-6783783 Reactome: R-HSA-6785807 Reactome: R-HSA-8957275
Cellular Localisation	Secreted
Alternative CLIA Names	Metalloproteinase Inhibitor 1 CLIA kit Erythroid-Potentiating Activity CLIA kit Epa CLIA kit Fibroblast Collagenase Inhibitor CLIA kit Collagenase Inhibitor CLIA kit Tissue Inhibitor Of Metalloproteinases 1 CLIA kit Timp-1 CLIA kit TIMP1 CLIA kit CLGI CLIA kit TIMP CLIA kit
Specificity	This kit recognizes Human TIMP-1 in samples. No significant cross-reactivity or interference between Human TIMP-1 and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are

Information sourced from Uniprot.org

Item Specifications Storage

Micro CLIA Plate (Dismountable)	96T: 8 wells ×12 strips strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial	-20℃, 6 months
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 60 μL	-20℃, 6 months
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 60 μL	-20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL	2-8°C, 6 months
HRP Conjugate Diluent	1 vial, 14 mL	2-8°C, 6 months
Concentrated Wash Buffer (25×)	1 vial, 30 mL	2-8°C, 6 months
Substrate Reagent A	1 vial, 5 mL	2-8℃ (Protect from light)
Substrate Reagent B	1 vial, 5 mL	2-8℃ (Protect from light)
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

Sample Type Range (%) Average Recovery (%)

Serum(n=8)	90-102	95
EDTA plasma(n=8)	96-114	104
Cell culture media(n=8)	87-101	92

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision

Sample	1.00	2.00	3.00	1.00	2.00	3.00
n	20.00	20.00	20.00	20.00	20.00	20.00
Mean (pg/mL)	103.06	280.80	875.15	92.92	285.71	946.10
Standard deviation	8.27	33.39	55.05	9.23	28.80	98.96
CV (%)	8.02	11.89	6.29	9.93	10.08	10.46

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Human TIMP1 (Metalloproteinase inhibitor 1) CLIA Kit (STJC0000146)