Anti-Cleaved-KLK8-V33 antibody (14-63 aa) (STJ90055) STJ90055 上海玉博生物科技有限公司

Anti-Cleaved-KLK8-V33 antibody (14-63 aa) (STJ90055)

简单介绍

Anti-Cleaved-KLK8-V33 antibody (14-63 aa) (STJ90055)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cleaved-Kallikrein-8-V33 (14-63 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 ELISA 1:10000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	KLK8
Gene ID:	11202
Uniprot ID:	KLK8_HUMAN
Immunogen Region:	14-63 aa
Specificity:	Cleaved-KLK8 (V33) Polyclonal Antibody detects endogenous levels of fragment of activated KLK8 protein resulting from cleavage adjacent to V33.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human Neuropsin at the amino acid range 14-63

Function	Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury.
Protein Name	Kallikrein-8 Hk8 Neuropsin Np Ovasin Serine Protease 19 Serine Protease Tadg-14 Tumor-Associated Differentially Expressed Gene 14 Protein
Database Links	Reactome: R-HSA-6809371
Cellular Localisation	Secreted Cytoplasm Shows A Cytoplasmic Distribution In The Keratinocytes
Alternative Antibody Names	Anti-Kallikrein-8 antibody Anti-Hk8 antibody Anti-Neuropsin antibody Anti-Np antibody Anti-Ovasin antibody Anti-Serine Protease 19 antibody Anti-Serine Protease Tadg-14 antibody Anti-Tumor-Associated Differentially Expressed Gene 14 Protein antibody Anti-KLK8 antibody Anti-NRPN antibody Anti-PRSS19 antibody Anti-TADG14 antibody Anti-UNQ283 antibody Anti-PRO322 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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