Anti-Cleaved-MMP20-Tyr108 antibody (107-108) (STJA0005891) STJA0005891 上海玉博生物科技有限公司

Anti-Cleaved-MMP20-Tyr108 antibody (107-108) (STJA0005891)

简单介绍

Anti-Cleaved-MMP20-Tyr108 antibody (107-108) (STJA0005891)

产品描述

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cleaved-Matrix metalloproteinase-20-Tyr108 (107-108) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 IHC-p 1:50-300
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	MMP20
Gene ID:	9313
Uniprot ID:	MMP20_HUMAN
Immunogen Region:	107-108
Specificity:	This antibody detects endogenous levels of Human, Mouse, Rat MMP20 (Cleaved-Tyr108, protein was cleaved amino acid sequence between 107-108 )
Immunogen:	Synthesized peptide derived from human MMP20 (Cleaved-Tyr108)

Tissue Specificity	Expressed specifically in the enamel organ.
Post Translational Modifications	Autoactivates at least at the 107-Asn-\|-Tyr-108 site.
Function	Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Asn-\|-Phe-361' site.
Protein Name	Matrix Metalloproteinase-20 Mmp-20 Enamel Metalloproteinase Enamelysin
Database Links	Reactome: R-HSA-1442490 Reactome: R-HSA-1474228 Reactome: R-HSA-2022090
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Matrix Metalloproteinase-20 antibody Anti-Mmp-20 antibody Anti-Enamel Metalloproteinase antibody Anti-Enamelysin antibody Anti-MMP20 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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