Anti-Cleaved-MMP9-Phe107 antibody (106-107) (STJA0005897) STJA0005897 上海玉博生物科技有限公司

Anti-Cleaved-MMP9-Phe107 antibody (106-107) (STJA0005897)

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产品名称：Anti-Cleaved-MMP9-Phe107 antibody (106-107) (STJA0005897)
产品型号：STJA0005897
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-Cleaved-MMP9-Phe107 antibody (106-107) (STJA0005897)

产品描述

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cleaved-Matrix metalloproteinase-9-Phe107 (106-107) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 IHC-p 1:50-300
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	MMP9
Gene ID:	4318
Uniprot ID:	MMP9_HUMAN
Immunogen Region:	106-107
Specificity:	This antibody detects endogenous levels of Human MMP9 (Cleaved-Phe107, protein was cleaved amino acid sequence between 106-107 )
Immunogen:	Synthesized peptide derived from human MMP9 (Cleaved-Phe107)

Tissue Specificity	Detected in neutrophils (at protein level). Produced by normal alveolar macrophages and granulocytes.
Post Translational Modifications	Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9. N- and O-glycosylated.
Function	Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-\|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
Protein Name	Matrix Metalloproteinase-9 Mmp-9 92 Kda Gelatinase 92 Kda Type Iv Collagenase Gelatinase B Gelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9
Database Links	Reactome: R-HSA-1433557 Reactome: R-HSA-1442490 Reactome: R-HSA-1474228 Reactome: R-HSA-1592389 Reactome: R-HSA-2022090 Reactome: R-HSA-3928665 Reactome: R-HSA-6785807 Reactome: R-HSA-6798695 Reactome: R-HSA-9009391
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Matrix Metalloproteinase-9 antibody Anti-Mmp-9 antibody Anti-92 Kda Gelatinase antibody Anti-92 Kda Type Iv Collagenase antibody Anti-Gelatinase B antibody Anti-Gelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 antibody Anti-MMP9 antibody Anti-CLG4B antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-Cleaved-MMP9-Phe107 antibody (106-107) (STJA0005897)