Anti-CCNB1IP1 antibody (1-50) (STJ119107) STJ119107 上海玉博生物科技有限公司

Anti-CCNB1IP1 antibody (1-50) (STJ119107)

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产品名称：Anti-CCNB1IP1 antibody (1-50) (STJ119107)
产品型号：STJ119107
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CCNB1IP1 antibody (1-50) (STJ119107)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CCNB1IP1 (1-50) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CCNB1IP1
Gene ID:	57820
Uniprot ID:	CIP1_HUMAN
Immunogen Region:	1-50
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 1-50 of human CCNB1IP1 (NP_878269.1).
Immunogen Sequence:	MSLCEDMLLCNYRKCRIKLS GYAWVTACSHIFCDQHGSGE FSRSPAICPA

Tissue Specificity	Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung.
Post Translational Modifications	Ubiquitinated.autoubiquitinated. Phosphorylated by CDK1 on serine or threonine residues (in vitro).
Function	Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL-gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over. Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis. E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.
Protein Name	E3 Ubiquitin-Protein Ligase Ccnb1ip1 Cyclin-B1-Interacting Protein 1 Human Enhancer Of Invasion 10 Ring-Type E3 Ubiquitin Transferase Ccnb1ip1
Cellular Localisation	Nucleus Chromosome Associates To The Synaptonemal Complex
Alternative Antibody Names	Anti-E3 Ubiquitin-Protein Ligase Ccnb1ip1 antibody Anti-Cyclin-B1-Interacting Protein 1 antibody Anti-Human Enhancer Of Invasion 10 antibody Anti-Ring-Type E3 Ubiquitin Transferase Ccnb1ip1 antibody Anti-CCNB1IP1 antibody Anti-C14orf18 antibody Anti-HEI10 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CCNB1IP1 antibody (1-50) (STJ119107)