Human TMPRSS4 (Transmembrane Protease, Serine 4) Sandwich ELISA Kit Ready-To-Use (STJE0019046) STJE0019046 上海玉博生物科技有限公司

Human TMPRSS4 (Transmembrane Protease, Serine 4) Sandwich ELISA Kit Ready-To-Use (STJE0019046)

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产品名称：Human TMPRSS4 (Transmembrane Protease, Serine 4) Sandwich ELISA Kit Ready-To-Use (STJE0019046)
产品型号：STJE0019046
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human TMPRSS4 (Transmembrane Protease, Serine 4) Sandwich ELISA Kit Ready-To-Use (STJE0019046)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.062ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This TMPRSS4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	TMPRSS4
Gene ID:	56649
Uniprot ID:	TMPS4_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract. Coexpressed with ACE2 within mature enterocytes.
Post Translational Modifications	Proteolytically processed.probably by an autocatalytic mechanism.
Function	Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC. (Microbial infection) In gut epithelial cells, facilitates human coronavirus SARS-CoV-2 infection through, at least, the cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry.
Protein Name	Transmembrane Protease Serine 4 Channel-Activating Protease 2 Caph2 Membrane-Type Serine Protease 2 Mt-Sp2 Cleaved Into - Transmembrane Protease Serine 4 Catalytic Chain
Database Links
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein Transmembrane Protease Serine 4 Catalytic Chain: Secreted Activated By Cleavage And Secreted
Alternative ELISA Names	Transmembrane Protease Serine 4 ELISA kit Channel-Activating Protease 2 ELISA kit Caph2 ELISA kit Membrane-Type Serine Protease 2 ELISA kit Mt-Sp2 Cleaved Into - Transmembrane Protease Serine 4 Catalytic Chain ELISA kit TMPRSS4 ELISA kit TMPRSS3 ELISA kit UNQ776 ELISA kit PRO1570 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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