Anti-Cleaved-PRSS8-Ile45, Heavy Chain antibody (44-45) (STJA0005908) STJA0005908 上海玉博生物科技有限公司

Anti-Cleaved-PRSS8-Ile45, Heavy Chain antibody (44-45) (STJA0005908)

简单介绍

Anti-Cleaved-PRSS8-Ile45, Heavy Chain antibody (44-45) (STJA0005908)

产品描述

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cleaved-Prostasin-Ile45, Heavy Chain (44-45) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 IHC-p 1:50-300
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	PRSS8
Gene ID:	5652
Uniprot ID:	PRSS8_HUMAN
Immunogen Region:	44-45
Specificity:	This antibody detects endogenous levels of Human, Mouse, Rat PRSS8 (heavy chain, Cleaved-Ile45, protein was cleaved amino acid sequence between 44-45 )
Immunogen:	Synthesized peptide derived from human PRSS8 (heavy chain, Cleaved-Ile45)

Tissue Specificity	Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid.
Function	Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).
Protein Name	Prostasin Channel-Activating Protease 1 Cap1 Serine Protease 8 Cleaved Into - Prostasin Light Chain - Prostasin Heavy Chain
Database Links	Reactome: R-HSA-6809371
Cellular Localisation	Prostasin: Cell Membrane Single-Pass Membrane Protein Prostasin Light Chain: Secreted Extracellular Space Found In The Seminal Fluid Secreted After Cleavage Of Its C-Terminus Prostasin Heavy Chain: Secreted
Alternative Antibody Names	Anti-Prostasin antibody Anti-Channel-Activating Protease 1 antibody Anti-Cap1 antibody Anti-Serine Protease 8 Cleaved Into - Prostasin Light Chain - Prostasin Heavy Chain antibody Anti-PRSS8 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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