Anti-Cleaved-SPTAN1-D1185 antibody (1136-1185 aa) (STJ90073) STJ90073 上海玉博生物科技有限公司

Anti-Cleaved-SPTAN1-D1185 antibody (1136-1185 aa) (STJ90073)

简单介绍

Anti-Cleaved-SPTAN1-D1185 antibody (1136-1185 aa) (STJ90073)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cleaved-Spectrin alpha chain, non-erythrocytic 1-D1185 (1136-1185 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 ELISA 1:10000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	SPTAN1
Gene ID:	6709
Uniprot ID:	SPTN1_HUMAN
Immunogen Region:	1136-1185 aa
Specificity:	Cleaved-Spectrin Alpha II (D1185) Polyclonal Antibody detects endogenous levels of fragment of activated Spectrin Alpha II protein resulting from cleavage adjacent to D1185.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human SPTA2 at the amino acid range 1136-1185

Function	Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Protein Name	Spectrin Alpha Chain - Non-Erythrocytic 1 Alpha-Ii Spectrin Fodrin Alpha Chain Spectrin - Non-Erythroid Alpha Subunit
Database Links	Reactome: R-HSA-264870 Reactome: R-HSA-373753 Reactome: R-HSA-375165 Reactome: R-HSA-445095 Reactome: R-HSA-5673001 Reactome: R-HSA-6798695 Reactome: R-HSA-6807878 Reactome: R-HSA-9013420 Reactome: R-HSA-9013424 Reactome: R-HSA-9662360 Reactome: R-HSA-9662361
Cellular Localisation	Cytoplasm Cytoskeleton Cell Cortex Expressed Along The Cell Membrane In Podocytes And Presumptive Tubule Cells During Glomerulogenesis And Is Expressed Along Lateral Cell Margins In Tubule Cells
Alternative Antibody Names	Anti-Spectrin Alpha Chain - Non-Erythrocytic 1 antibody Anti-Alpha-Ii Spectrin antibody Anti-Fodrin Alpha Chain antibody Anti-Spectrin - Non-Erythroid Alpha Subunit antibody Anti-SPTAN1 antibody Anti-NEAS antibody Anti-SPTA2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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