Anti-CLEC12A antibody (66-265) (STJ28006) STJ28006 上海玉博生物科技有限公司

Anti-CLEC12A antibody (66-265) (STJ28006)

简单介绍

Anti-CLEC12A antibody (66-265) (STJ28006)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CLEC12A (66-265) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CLEC12A
Gene ID:	160364
Uniprot ID:	CL12A_HUMAN
Immunogen Region:	66-265
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 66-265 of human CLEC12A (NP_612210.4).
Immunogen Sequence:	VTLKIEMKKMNKLQNISEEL QRNISLQLMSNMNISNKIRN LSTTLQTIATKLCRELYSKE QEHKCKPCPRRWIWHKDSCY FLSDDVQTWQESKMACAAQN ASLLKINNKNALEFIKSQSR SYDYWLGLSPEEDSTRGMRV DNIINSSAWVIRNAPDLNNM YCGYINRLYVQYYHCTYKKR MICEKMANPVQLGSTYFREA

Tissue Specificity	Detected in normal myeloid cells and in acute myeloid leukemia cells. Detected in neutrophils, eosinophils, monocytes and dendritic cells. Detected in spleen macrophage-rich red pulp and in lymph node (at protein level). Detected in peripheral blood leukocytes, dendritic cells, bone marrow, monocytes, mononuclear leukocytes and macrophages.
Post Translational Modifications	Highly N-glycosylated. Glycosylation varies between cell types.
Function	Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
Protein Name	C-Type Lectin Domain Family 12 Member A C-Type Lectin-Like Molecule 1 Cll-1 Dendritic Cell-Associated Lectin 2 Dcal-2 Myeloid Inhibitory C-Type Lectin-Like Receptor Micl Cd Antigen Cd371
Database Links	Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein Ligand Binding Leads To Internalization
Alternative Antibody Names	Anti-C-Type Lectin Domain Family 12 Member A antibody Anti-C-Type Lectin-Like Molecule 1 antibody Anti-Cll-1 antibody Anti-Dendritic Cell-Associated Lectin 2 antibody Anti-Dcal-2 antibody Anti-Myeloid Inhibitory C-Type Lectin-Like Receptor antibody Anti-Micl antibody Anti-Cd Antigen Cd371 antibody Anti-CLEC12A antibody Anti-CLL1 antibody Anti-DCAL2 antibody Anti-MICL antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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