Anti-CLEC1B antibody (STJ192290) STJ192290 上海玉博生物科技有限公司

Anti-CLEC1B antibody (STJ192290)

简单介绍

Anti-CLEC1B antibody (STJ192290)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-C-type lectin domain family 1 member B is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CLEC1B
Gene ID:	51266
Uniprot ID:	CLC1B_HUMAN
Specificity:	CLC1B Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from part of the human protein

Post Translational Modifications	Glycosylated. Phosphorylated on tyrosine residue in response to rhodocytin binding.
Function	C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN. After ligand activation, signals via sequential activation of SRC and SYK tyrosine kinases leading to activation of PLCG2. (Microbial infection) Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (SYK) and initiation of downstream tyrosine phosphorylation events and activation of PLCG2. (Microbial infection) Acts as an attachment factor for Human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets.
Protein Name	C-Type Lectin Domain Family 1 Member B C-Type Lectin-Like Receptor 2 Clec-2
Database Links	Reactome: R-HSA-114604 Reactome: R-HSA-9707616
Cellular Localisation	Membrane Single-Pass Type Ii Membrane Protein
Alternative Antibody Names	Anti-C-Type Lectin Domain Family 1 Member B antibody Anti-C-Type Lectin-Like Receptor 2 antibody Anti-Clec-2 antibody Anti-CLEC1B antibody Anti-CLEC2 antibody Anti-UNQ721 antibody Anti-PRO1384 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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