Anti-CLEC4C antibody (45-213) (STJ115657) STJ115657 上海玉博生物科技有限公司

Anti-CLEC4C antibody (45-213) (STJ115657)

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产品名称：Anti-CLEC4C antibody (45-213) (STJ115657)
产品型号：STJ115657
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CLEC4C antibody (45-213) (STJ115657)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CLEC4C (45-213) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CLEC4C
Gene ID:	170482
Uniprot ID:	CLC4C_HUMAN
Immunogen Region:	45-213
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 45-213 of human CLEC4C (NP_569708.1).
Immunogen Sequence:	NFMYSKTVKRLSKLREYQQY HPSLTCVMEGKDIEDWSCCP TPWTSFQSSCYFISTGMQSW TKSQKNCSVMGADLVVINTR EEQDFIIQNLKRNSSYFLGL SDPGGRRHWQWVDQTPYNEN VTFWHSGEPNNLDERCAIIN FRSSEEWGWNDIHCHVPQKS ICKMKKIYI

Tissue Specificity	Expressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not with TNF-alpha.
Function	Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
Protein Name	C-Type Lectin Domain Family 4 Member C Blood Dendritic Cell Antigen 2 Bdca-2 C-Type Lectin Superfamily Member 7 Dendritic Lectin Cd Antigen Cd303
Database Links	Reactome: R-HSA-5621480 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein
Alternative Antibody Names	Anti-C-Type Lectin Domain Family 4 Member C antibody Anti-Blood Dendritic Cell Antigen 2 antibody Anti-Bdca-2 antibody Anti-C-Type Lectin Superfamily Member 7 antibody Anti-Dendritic Lectin antibody Anti-Cd Antigen Cd303 antibody Anti-CLEC4C antibody Anti-BDCA2 antibody Anti-CLECSF11 antibody Anti-CLECSF7 antibody Anti-DLEC antibody Anti-HECL antibody Anti-UNQ9361 antibody Anti-PRO34150 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CLEC4C antibody (45-213) (STJ115657)