Anti-CCNDBP1 antibody (1-360) (STJ115687) STJ115687 上海玉博生物科技有限公司

Anti-CCNDBP1 antibody (1-360) (STJ115687)

简单介绍

Anti-CCNDBP1 antibody (1-360) (STJ115687)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CCNDBP1 (1-360) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CCNDBP1
Gene ID:	23582
Uniprot ID:	CCDB1_HUMAN
Immunogen Region:	1-360
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human CCNDBP1 (NP_036274.3).
Immunogen Sequence:	MASATAPAAAVPTLASPLEQ LRHLAEELRLLLPRVRVGEA QETTEEFNREMFWRRLNEAA VTVSREATTLTIVFSQLPLP SPQETQKFCEQVHAAIKAFI AVYYLLPKDQGITLRKLVRG ATLDIVDGMAQLMEVLSVTP TQSPENNDLISYNSVWVACQ QMPQIPRDNKAAALLMLTKN VDFVKDAHEEMEQAVEECDP YSGLLNDTEENNSDNHNHED DVLGFPSNQDLYWSEDDQE

Tissue Specificity	Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
Post Translational Modifications	Phosphorylated.
Function	May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
Protein Name	Cyclin-D1-Binding Protein 1 Grap2 And Cyclin-D-Interacting Protein Human Homolog Of Maid
Cellular Localisation	Cytoplasm Nucleus
Alternative Antibody Names	Anti-Cyclin-D1-Binding Protein 1 antibody Anti-Grap2 And Cyclin-D-Interacting Protein antibody Anti-Human Homolog Of Maid antibody Anti-CCNDBP1 antibody Anti-DIP1 antibody Anti-GCIP antibody Anti-HHM antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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