Anti-CLNS1A antibody (1-237) (STJ118480) STJ118480 上海玉博生物科技有限公司

Anti-CLNS1A antibody (1-237) (STJ118480)

如果您对该产品感兴趣的话，可以
产品名称：Anti-CLNS1A antibody (1-237) (STJ118480)
产品型号：STJ118480
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CLNS1A antibody (1-237) (STJ118480)

产品描述

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CLNS1A (1-237) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:50-1:100
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CLNS1A
Gene ID:	1207
Uniprot ID:	ICLN_HUMAN
Immunogen Region:	1-237
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-237 of human CLNS1A (NP_001284.1).
Immunogen Sequence:	MSFLKSFPPPGPAEGLLRQQ PDTEAVLNGKGLGTGTLYIA ESRLSWLDGSGLGFSLEYPT ISLHALSRDRSDCLGEHLYV MVNAKFEEESKEPVADEEEE DSDDDVEPITEFRFVPSDKS ALEAMFTAMCECQALHPDPE DEDSDDYDGEEYDVEAHEQG QGDIPTFYTYEEGLSHLTAE GQATLERLEGMLSQSVSSQY NMAGVRTEDSIRDYEDGMEV DTTPTVAGQFEDADVDH

Function	Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins. Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
Protein Name	Methylosome Subunit Picln Chloride Channel - Nucleotide Sensitive 1a Chloride Conductance Regulatory Protein Icln I(Cln Chloride Ion Current Inducer Protein Clci Reticulocyte Picln
Database Links	Reactome: R-HSA-191859
Cellular Localisation	Cytoplasm Cytosol Nucleus Cytoskeleton A Small Fraction Is Also Associated With The Cytoskeleton
Alternative Antibody Names	Anti-Methylosome Subunit Picln antibody Anti-Chloride Channel - Nucleotide Sensitive 1a antibody Anti-Chloride Conductance Regulatory Protein Icln antibody Anti-I(Cln antibody Anti-Chloride Ion Current Inducer Protein antibody Anti-Clci antibody Anti-Reticulocyte Picln antibody Anti-CLNS1A antibody Anti-CLCI antibody Anti-ICLN antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Anti-CLNS1A antibody (1-237) (STJ118480)