Anti-CLPP antibody (1-277) (STJ11104472) STJ11104472 上海玉博生物科技有限公司

Anti-CLPP antibody (1-277) (STJ11104472)

简单介绍

Anti-CLPP antibody (1-277) (STJ11104472)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Atp-Dependent Clp Protease Proteolytic Subunit-Mitochondrial (1-277) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CLPP
Gene ID:	8192
Uniprot ID:	CLPP_HUMAN
Immunogen Region:	1-277
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human CLPP (NP_006003.1).
Immunogen Sequence:	MWPGILVGGARVASCRYPAL GPRLAAHFPAQRPPQRTLQN GLALQRCLHATATRALPLIP IVVEQTGRGERAYDIYSRLL RERIVCVMGPIDDSVASLVI AQLLFLQSESNKKPIHMYIN SPGGVVTAGLAIYDTMQYIL NPICTWCVGQAASMGSLLLA AGTPGMRHSLPNSRIMIHQP SGGARGQATDIAIQAEEIMK LKKQLYNIYAKHTKQSLQVI ESAMERDRYMSPMEAQEFG

Tissue Specificity	Detected in liver (at protein level). Predominantly expressed in skeletal muscle. Intermediate levels in heart, liver and pancreas. Low in brain, placenta, lung and kidney.
Function	Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. Cleaves PINK1 in the mitochondrion.
Protein Name	Atp-Dependent Clp Protease Proteolytic Subunit - Mitochondrial Endopeptidase Clp
Cellular Localisation	Mitochondrion Matrix
Alternative Antibody Names	Anti-Atp-Dependent Clp Protease Proteolytic Subunit - Mitochondrial antibody Anti-Endopeptidase Clp antibody Anti-CLPP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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