Anti-CLPX antibody (534-633) [S4090RM] (STJ11104090) STJ11104090 上海玉博生物科技有限公司

Anti-CLPX antibody (534-633) [S4090RM] (STJ11104090)

简单介绍

Anti-CLPX antibody (534-633) [S4090RM] (STJ11104090)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-Atp-Dependent Clp Protease Atp-Binding Subunit Clpx-Like-Mitochondrial (534-633) is suitable for use in Western Blot research applications.

Clonality:	Monoclonal
Clone ID:	S4090RM
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:100-1:500
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CLPX
Gene ID:	10845
Uniprot ID:	CLPX_HUMAN
Immunogen Region:	534-633
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 534-633 of human CLPX (O76031).
Immunogen Sequence:	SMDKCELNVTEDALKAIARL ALERKTGARGLRSIMEKLLL EPMFEVPNSDIVCVEVDKEV VEGKKEPGYIRAPTKESSEE EYDSGVEEEGWPRQADAANS

Tissue Specificity	Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas.
Function	ATP-dependent specificity component of the Clp protease complex. Hydrolyzes ATP. Targets specific substrates for degradation by the Clp complex. Can perform chaperone functions in the absence of CLPP. Enhances the DNA-binding activity of TFAM and is required for maintaining a normal mitochondrial nucleoid structure. ATP-dependent unfoldase that stimulates the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase, thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis. Important for efficient erythropoiesis through up-regulation of heme biosynthesis.
Protein Name	Atp-Dependent Clp Protease Atp-Binding Subunit Clpx-Like - Mitochondrial
Cellular Localisation	Mitochondrion Mitochondrion Matrix Mitochondrion Nucleoid
Alternative Antibody Names	Anti-Atp-Dependent Clp Protease Atp-Binding Subunit Clpx-Like - Mitochondrial antibody Anti-CLPX antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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