Anti-CCNY antibody (270-350 aa) (STJ191671) STJ191671 上海玉博生物科技有限公司

Anti-CCNY antibody (270-350 aa) (STJ191671)

简单介绍

Anti-CCNY antibody (270-350 aa) (STJ191671)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cyclin-Y (270-350 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CCNY
Gene ID:	219771
Uniprot ID:	CCNY_HUMAN
Immunogen Region:	270-350 aa
Specificity:	CCNY Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from the human protein at the amino acid range 270-350

Post Translational Modifications	Ubiquitinated.leading to its degradation. Heavily phosphorylated. Phosphorylation at Ser-71 and Ser-73 by CDK14 is enhanced during the G2 and M cell cycle phases, and creates a phosphodegron triggering SCF-dependent ubiquitination.
Function	Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Protein Name	Cyclin-Y Cyc-Y Cyclin Box Protein 1 Cyclin Fold Protein 1 Cyclin-X
Cellular Localisation	Cell Membrane Lipid-Anchor Cytoplasmic Side Isoform 3: Nucleus
Alternative Antibody Names	Anti-Cyclin-Y antibody Anti-Cyc-Y antibody Anti-Cyclin Box Protein 1 antibody Anti-Cyclin Fold Protein 1 antibody Anti-Cyclin-X antibody Anti-CCNY antibody Anti-C10orf9 antibody Anti-CBCP1 antibody Anti-CFP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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