Anti-CNGA4 antibody (416-575) (STJ116920) STJ116920 上海玉博生物科技有限公司

Anti-CNGA4 antibody (416-575) (STJ116920)

简单介绍

Anti-CNGA4 antibody (416-575) (STJ116920)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CNGA4 (416-575) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CNGA4
Gene ID:	1262
Uniprot ID:	CNGA4_HUMAN
Immunogen Region:	416-575
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 416-575 of human CNGA4 (NP_001032406.1).
Immunogen Sequence:	ISIINIKGNMSGNRRTANIK SLGYSDLFCLSKEDLREVLS EYPQAQTIMEEKGREILLKM NKLDVNAEAAEIALQEATES RLRGLDQQLDDLQTKFARLL AELESSALKIAYRIERLEWQ TREWPMPEDLAEADDEGEPE EGTSKDEEGRASQEGPPGPE

Function	Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.
Protein Name	Cyclic Nucleotide-Gated Cation Channel Alpha-4 Cyclic Nucleotide-Gated Channel Alpha-4 Cng Channel Alpha-4 Cng-4 Cng4
Database Links	Reactome: R-HSA-381753 Reactome: R-HSA-5620916
Cellular Localisation	Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Cyclic Nucleotide-Gated Cation Channel Alpha-4 antibody Anti-Cyclic Nucleotide-Gated Channel Alpha-4 antibody Anti-Cng Channel Alpha-4 antibody Anti-Cng-4 antibody Anti-Cng4 antibody Anti-CNGA4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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