Human TSG101 (Tumor Susceptibility Gene 101) Sandwich ELISA Kit (STJE0012835) STJE0012835 上海玉博生物科技有限公司

Human TSG101 (Tumor Susceptibility Gene 101) Sandwich ELISA Kit (STJE0012835)

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产品名称：Human TSG101 (Tumor Susceptibility Gene 101) Sandwich ELISA Kit (STJE0012835)
产品型号：STJE0012835
产品展商：ST john's laboratory
产品文档：无相关文档

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Human TSG101 (Tumor Susceptibility Gene 101) Sandwich ELISA Kit (STJE0012835)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.105ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This TSG101 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	TSG101
Gene ID:	7251
Uniprot ID:	TS101_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Heart, brain, placenta, lung, liver, skeletal, kidney and pancreas.
Post Translational Modifications	Monoubiquitinated at multiple sites by LRSAM1 and by MGRN1. Ubiquitination inactivates it, possibly by regulating its shuttling between an active membrane-bound protein and an inactive soluble form. Ubiquitination by MGRN1 requires the presence of UBE2D1.
Function	Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis.the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-ST-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan. It may also play a role in the extracellular release of microvesicles that differ from the exosomes.
Protein Name	Tumor Susceptibility Gene 101 Protein Escrt-I Complex Subunit Tsg101
Database Links	Reactome: R-HSA-162588 Reactome: R-HSA-174490 Reactome: R-HSA-917729 Reactome: R-HSA-9610379 Reactome: R-HSA-9615710
Cellular Localisation	Cytoplasm Early Endosome Membrane Peripheral Membrane Protein Cytoplasmic Side Late Endosome Membrane Cytoskeleton Microtubule Organizing Center Centrosome Midbody Midbody Ring Nucleus Mainly Cytoplasmic Membrane-Associated When Active And Soluble When Inactive Nuclear Localization Is Cell Cycle-Dependent Interaction With Cep55 Is Required For Localization To The Midbody During Cytokinesis
Alternative ELISA Names	Tumor Susceptibility Gene 101 Protein ELISA kit Escrt-I Complex Subunit Tsg101 ELISA kit TSG101 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human TSG101 (Tumor Susceptibility Gene 101) Sandwich ELISA Kit (STJE0012835)