Anti-CNOT2 antibody (341-540) (STJ114698) STJ114698 上海玉博生物科技有限公司

Anti-CNOT2 antibody (341-540) (STJ114698)

简单介绍

Anti-CNOT2 antibody (341-540) (STJ114698)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CNOT2 (341-540) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CNOT2
Gene ID:	4848
Uniprot ID:	CNOT2_HUMAN
Immunogen Region:	341-540
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 341-540 of human CNOT2 (NP_055330.1).
Immunogen Sequence:	GRVTNIPQGMVTDQFGMIGL LTFIRAAETDPGMVHLALGS DLTTLGLNLNSPENLYPKFA SPWASSPCRPQDIDFHVPSE YLTNIHIRDKLAAIKLGRYG EDLLFYLYYMNGGDVLQLLA AVELFNRDWRYHKEERVWIT RAPGMEPTMKTNTYERGTYY FFDCLNWRKVAKEFHLEYDK LEERPHLPSTFNYNPAQQAF

Tissue Specificity	Ubiquitous. Highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes.
Function	Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation.the repressive function may specifically involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of embryonic stem (ES) cell identity.
Protein Name	Ccr4-Not Transcription Complex Subunit 2 Ccr4-Associated Factor 2
Database Links	Reactome: R-HSA-429947 Reactome: R-HSA-6804115
Cellular Localisation	Cytoplasm Nucleus
Alternative Antibody Names	Anti-Ccr4-Not Transcription Complex Subunit 2 antibody Anti-Ccr4-Associated Factor 2 antibody Anti-CNOT2 antibody Anti-CDC36 antibody Anti-NOT2 antibody Anti-HSPC131 antibody Anti-MSTP046 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

产品目录