Anti-CD10 antibody (52-750) [S5672RM] (STJ11105672) STJ11105672 上海玉博生物科技有限公司

Anti-CD10 antibody (52-750) [S5672RM] (STJ11105672)

简单介绍

Anti-CD10 antibody (52-750) [S5672RM] (STJ11105672)

产品描述

Host:	Rabbit
Applications:	WB/FC
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-CD10 (52-750) is suitable for use in Western Blot and Flow Cytometry research applications.

Clonality:	Monoclonal
Clone ID:	S5672RM
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:1000-1:5000 FC 1:500-1:1000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	Mme
Gene ID:	17380
Uniprot ID:	NEP_MOUSE
Immunogen Region:	52-750
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 52-750 of mouse CD10 (NP_032630.2).
Immunogen Sequence:	YDDGICKSSDCIKSAARLIQ NMDASVEPCTDFFKYACGGW LKRNVIPETSSRYSNFDILR DELEVILKDVLQEPKTEDIV AVQKAKTLYRSCINESAIDS RGGQPLLKLLPDIYGWPVAS DNWDQTYGTSWTAEKSIAQL NSKYGKKVLINFFVGTDDKN STQHIIHFDQPRLGLPSRDY YECTGIYKEACTAYVDFMIS VARLIRQEQSLPIDENQLSL EMNKVMELEKEIANATTKP

Post Translational Modifications	Myristoylation is a determinant of membrane targeting. Glycosylation at Asn-628 is necessary both for surface expression and neutral endopeptidase activity.
Function	Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of the atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Protein Name	Neprilysin Atriopeptidase Enkephalinase Neutral Endopeptidase 24.11 Nep Neutral Endopeptidase Skin Fibroblast Elastase Sfe Cd Antigen Cd10
Database Links	Reactome: R-MMU-2022377 Reactome: -MMU-5578768 Reactome: -MMU-6798695
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein
Alternative Antibody Names	Anti-Neprilysin antibody Anti-Atriopeptidase antibody Anti-Enkephalinase antibody Anti-Neutral Endopeptidase 24.11 antibody Anti-Nep antibody Anti-Neutral Endopeptidase antibody Anti-Skin Fibroblast Elastase antibody Anti-Sfe antibody Anti-Cd Antigen Cd10 antibody Anti-Mme antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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