Human UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats) Sandwich ELISA Kit (STJE0012879) STJE0012879 上海玉博生物科技有限公司

Human UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats) Sandwich ELISA Kit (STJE0012879)

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产品名称：Human UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats) Sandwich ELISA Kit (STJE0012879)
产品型号：STJE0012879
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats) Sandwich ELISA Kit (STJE0012879)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.132ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This UACA Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	UACA
Gene ID:	55075
Uniprot ID:	UACA_HUMAN
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Highly expressed in skeletal muscle, heart, kidney and pancreas. Expressed in choroid, retina and epidermal melanocytes. Expressed in eye muscles and thyroid follicular cells.
Post Translational Modifications
Function	Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1. Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation.
Protein Name	Uveal Autoantigen With Coiled-Coil Domains And Ankyrin Repeats
Database Links	Reactome: R-HSA-9013407 Reactome: R-HSA-9627069
Cellular Localisation	Nucleus Cytoplasm Cytoskeleton Expressed Diffusely In Cytoplasm
Alternative ELISA Names	Uveal Autoantigen With Coiled-Coil Domains And Ankyrin Repeats ELISA kit UACA ELISA kit KIAA1561 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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