Human UBE2A (Ubiquitin Conjugating Enzyme E2A) Sandwich ELISA Kit Ready-To-Use (STJE0019281) STJE0019281 上海玉博生物科技有限公司

Human UBE2A (Ubiquitin Conjugating Enzyme E2A) Sandwich ELISA Kit Ready-To-Use (STJE0019281)

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产品名称：Human UBE2A (Ubiquitin Conjugating Enzyme E2A) Sandwich ELISA Kit Ready-To-Use (STJE0019281)
产品型号：STJE0019281
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human UBE2A (Ubiquitin Conjugating Enzyme E2A) Sandwich ELISA Kit Ready-To-Use (STJE0019281)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.081ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This UBE2A Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	UBE2A
Gene ID:	7319
Uniprot ID:	UBE2A_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Phosphorylation at Ser-120 by CDK9 increases activity towards histone H2B.
Function	Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.
Protein Name	Ubiquitin-Conjugating Enzyme E2 A E2 Ubiquitin-Conjugating Enzyme A Rad6 Homolog A Hr6a Hhr6a Ubiquitin Carrier Protein A Ubiquitin-Protein Ligase A
Database Links	Reactome: R-HSA-8866652 Reactome: R-HSA-8866654 Reactome: R-HSA-983168
Cellular Localisation
Alternative ELISA Names	Ubiquitin-Conjugating Enzyme E2 A ELISA kit E2 Ubiquitin-Conjugating Enzyme A ELISA kit Rad6 Homolog A ELISA kit Hr6a ELISA kit Hhr6a ELISA kit Ubiquitin Carrier Protein A ELISA kit Ubiquitin-Protein Ligase A ELISA kit UBE2A ELISA kit RAD6A ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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