Human UBE2L3 (Ubiquitin Conjugating Enzyme E2L3) Sandwich ELISA Kit Ready-To-Use (STJE0019284) STJE0019284 上海玉博生物科技有限公司

Human UBE2L3 (Ubiquitin Conjugating Enzyme E2L3) Sandwich ELISA Kit Ready-To-Use (STJE0019284)

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产品名称：Human UBE2L3 (Ubiquitin Conjugating Enzyme E2L3) Sandwich ELISA Kit Ready-To-Use (STJE0019284)
产品型号：STJE0019284
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human UBE2L3 (Ubiquitin Conjugating Enzyme E2L3) Sandwich ELISA Kit Ready-To-Use (STJE0019284)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.072ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This UBE2L3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	UBE2L3
Gene ID:	7332
Uniprot ID:	UB2L3_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Ubiquitous, with highest expression in testis.
Post Translational Modifications	Ubiquitinated. The alteration of UBE2L3 protein levels during the S-phase of the cell cycle is due to ubiquitin-dependent proteasomal degradation. Autoubiquitinated in vitro.
Function	Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PRKN, RNF31 and ARIH1, that function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.
Protein Name	Ubiquitin-Conjugating Enzyme E2 L3 E2 Ubiquitin-Conjugating Enzyme L3 L-Ubc Ubch7 Ubiquitin Carrier Protein L3 Ubiquitin-Conjugating Enzyme E2-F1 Ubiquitin-Protein Ligase L3
Database Links	Reactome: R-HSA-5357905 Reactome: R-HSA-5675482 Reactome: R-HSA-8866652 Reactome: R-HSA-8866654 Reactome: R-HSA-983168
Cellular Localisation	Nucleus Cytoplasm
Alternative ELISA Names	Ubiquitin-Conjugating Enzyme E2 L3 ELISA kit E2 Ubiquitin-Conjugating Enzyme L3 ELISA kit L-Ubc ELISA kit Ubch7 ELISA kit Ubiquitin Carrier Protein L3 ELISA kit Ubiquitin-Conjugating Enzyme E2-F1 ELISA kit Ubiquitin-Protein Ligase L3 ELISA kit UBE2L3 ELISA kit UBCE7 ELISA kit UBCH7 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human UBE2L3 (Ubiquitin Conjugating Enzyme E2L3) Sandwich ELISA Kit Ready-To-Use (STJE0019284)