Human UGCG (UDP Glucose Ceramide Glucosyltransferase) Sandwich ELISA Kit (STJE0012919) STJE0012919 上海玉博生物科技有限公司

Human UGCG (UDP Glucose Ceramide Glucosyltransferase) Sandwich ELISA Kit (STJE0012919)

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产品名称：Human UGCG (UDP Glucose Ceramide Glucosyltransferase) Sandwich ELISA Kit (STJE0012919)
产品型号：STJE0012919
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human UGCG (UDP Glucose Ceramide Glucosyltransferase) Sandwich ELISA Kit (STJE0012919)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.115ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This UGCG Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	UGCG
Gene ID:	7357
Uniprot ID:	CEGT_HUMAN
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Found in all tissues examined.
Post Translational Modifications
Function	Participates in the initial step of the glucosylceramide-based glycosphingolipid/GSL synthetic pathway at the cytosolic surface of the Golgi. Catalyzes the transfer of glucose from UDP-glucose to ceramide to produce glucosylceramide/GlcCer (such as beta-D-glucosyl-(11')-N-acylsphing-4-enine). GlcCer is the core component of glycosphingolipids/GSLs, amphipathic molecules consisting of a ceramide lipid moiety embedded in the outer leaflet of the membrane, linked to one of hundreds of different externally oriented oligosaccharide structures. Glycosphingolipids are essential components of membrane microdomains that mediate membrane trafficking and signal transduction, implicated in many fundamental cellular processes, including growth, differentiation, migration, morphogenesis, cell-to-cell and cell-to-matrix interactions. They are required for instance in the proper development and functioning of the nervous system. As an example of their role in signal transduction, they regulate the leptin receptor/LEPR in the leptin-mediated signaling pathway. They also play an important role in the establishment of the skin barrier regulating keratinocyte differentiation and the proper assembly of the cornified envelope. The biosynthesis of GSLs is also required for the proper intestinal endocytic uptake of nutritional lipids. Catalyzes the synthesis of xylosylceramide/XylCer (such as beta-D-xylosyl-(11')-N-acylsphing-4-enine) using UDP-Xyl as xylose donor.
Protein Name	Ceramide Glucosyltransferase Glct-1 Glucosylceramide Synthase Gcs Glycosylceramide Synthase Udp-Glucose Ceramide Glucosyltransferase Udp-Glucose -N-Acylsphingosine D-Glucosyltransferase
Database Links	Reactome: R-HSA-1660662
Cellular Localisation	Golgi Apparatus Membrane Multi-Pass Membrane Protein
Alternative ELISA Names	Ceramide Glucosyltransferase ELISA kit Glct-1 ELISA kit Glucosylceramide Synthase ELISA kit Gcs ELISA kit Glycosylceramide Synthase ELISA kit Udp-Glucose Ceramide Glucosyltransferase ELISA kit Udp-Glucose -N-Acylsphingosine D-Glucosyltransferase ELISA kit UGCG ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human UGCG (UDP Glucose Ceramide Glucosyltransferase) Sandwich ELISA Kit (STJE0012919)