Human UGT2B7 (UDP Glucuronosyltransferase 2 Family, Polypeptide B7) Sandwich ELISA Kit Ready-To-Use (STJE0019313) STJE0019313 上海玉博生物科技有限公司

Human UGT2B7 (UDP Glucuronosyltransferase 2 Family, Polypeptide B7) Sandwich ELISA Kit Ready-To-Use (STJE0019313)

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产品名称：Human UGT2B7 (UDP Glucuronosyltransferase 2 Family, Polypeptide B7) Sandwich ELISA Kit Ready-To-Use (STJE0019313)
产品型号：STJE0019313
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human UGT2B7 (UDP Glucuronosyltransferase 2 Family, Polypeptide B7) Sandwich ELISA Kit Ready-To-Use (STJE0019313)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.113ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This UGT2B7 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	UGT2B7
Gene ID:	7364
Uniprot ID:	UD2B7_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications
Function	UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds. Catalyzes the glucuronidation of endogenous steroid hormones such as androgens (epitestosterone, androsterone) and estrogens (estradiol, epiestradiol, estriol, catechol estrogens). Also regulates the levels of retinoic acid, a major metabolite of vitamin A involved in apoptosis, cellular growth and differentiation, and embryonic development. Contributes to bile acid (BA) detoxification by catalyzing the glucuronidation of BA substrates, which are natural detergents for dietary lipids absorption. Involved in the glucuronidation of the AGTR1 angiotensin receptor antagonist losartan, caderastan and zolarsatan, drugs which can inhibit the effect of angiotensin II. Also metabolizes mycophenolate, an immunosuppressive agent.
Protein Name	Udp-Glucuronosyltransferase 2b7 Udpgt 2b7 Ugt2b7 3 -4-Catechol Estrogen-Specific Udpgt Udp-Glucuronosyltransferase 2b9 Udpgt 2b9 Udpgth-2
Database Links	Reactome: R-HSA-156588 Reactome: R-HSA-9749641 Reactome: R-HSA-9757110
Cellular Localisation	Endoplasmic Reticulum Membrane Single-Pass Membrane Protein
Alternative ELISA Names	Udp-Glucuronosyltransferase 2b7 ELISA kit Udpgt 2b7 ELISA kit Ugt2b7 ELISA kit 3 -4-Catechol Estrogen-Specific Udpgt ELISA kit Udp-Glucuronosyltransferase 2b9 ELISA kit Udpgt 2b9 ELISA kit Udpgth-2 ELISA kit UGT2B7 ELISA kit UGTB2B9 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human UGT2B7 (UDP Glucuronosyltransferase 2 Family, Polypeptide B7) Sandwich ELISA Kit Ready-To-Use (STJE0019313)