Human USP14 (Ubiquitin Specific Peptidase 14) Sandwich ELISA Kit (STJE0012954) STJE0012954 上海玉博生物科技有限公司

Human USP14 (Ubiquitin Specific Peptidase 14) Sandwich ELISA Kit (STJE0012954)

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产品名称：Human USP14 (Ubiquitin Specific Peptidase 14) Sandwich ELISA Kit (STJE0012954)
产品型号：STJE0012954
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human USP14 (Ubiquitin Specific Peptidase 14) Sandwich ELISA Kit (STJE0012954)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.108ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This USP14 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	USP14
Gene ID:	9097
Uniprot ID:	UBP14_HUMAN
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications
Function	Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation.
Protein Name	Ubiquitin Carboxyl-Terminal Hydrolase 14 Deubiquitinating Enzyme 14 Ubiquitin Thioesterase 14 Ubiquitin-Specific-Processing Protease 14
Database Links	Reactome: R-HSA-5689880 Reactome: R-HSA-9758274
Cellular Localisation	Cytoplasm Cell Membrane Peripheral Membrane Protein
Alternative ELISA Names	Ubiquitin Carboxyl-Terminal Hydrolase 14 ELISA kit Deubiquitinating Enzyme 14 ELISA kit Ubiquitin Thioesterase 14 ELISA kit Ubiquitin-Specific-Processing Protease 14 ELISA kit USP14 ELISA kit TGT ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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