Anti-CD107a antibody [1D4B] {AF647} (STJA0004271) STJA0004271 上海玉博生物科技有限公司

Anti-CD107a antibody [1D4B] {AF647} (STJA0004271)

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产品名称：Anti-CD107a antibody [1D4B] {AF647} (STJA0004271)
产品型号：STJA0004271
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CD107a antibody [1D4B] {AF647} (STJA0004271)

产品描述

Host:	Rat
Applications:	FC
Reactivity:	Mouse
Note:	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description:	Rat monoclonal antibody anti-Lysosome-Associated Membrane Glycoprotein 1

Clonality:	Monoclonal
Clone ID:	1D4B
Conjugation:	AF647
Isotype:	IgG2ak
Formulation:	PBS with 0.05% Proclin300, 1% BSA
Storage Instruction:	Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.

Gene Symbol:	Lamp1
Gene ID:	16783
Uniprot ID:	LAMP1_MOUSE

Post Translational Modifications	O- and N-glycosylated.some of the N-glycans attached to LAMP-1 are polylactosaminoglycans.
Function	Lysosomal membrane glycoprotein which plays an important role in lysosome biogenesis, lysosomal pH regulation, autophagy and cholesterol homeostasis. Acts as an important regulator of lysosomal lumen pH regulation by acting as a direct inhibitor of the proton channel TMEM175, facilitating lysosomal acidification for optimal hydrolase activity. Also plays an important role in NK-cells cytotoxicity. Mechanistically, participates in cytotoxic granule movement to the cell surface and perforin trafficking to the lytic granule. In addition, protects NK-cells from degranulation-associated damage induced by their own cytotoxic granule content. Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
Protein Name	Lysosome-Associated Membrane Glycoprotein 1 Lamp-1 Lysosome-Associated Membrane Protein 1 120 Kda Lysosomal Membrane Glycoprotein Cd107 Antigen-Like Family Member A Lgp-120 Lysosomal Membrane Glycoprotein A Lgp-A P2b Cd Antigen Cd107a
Database Links	Reactome: R-MMU-6798695
Cellular Localisation	Lysosome Membrane Single-Pass Type I Membrane Protein Endosome Membrane Late Endosome Membrane Cell Membrane Cytolytic Granule Membrane This Protein Shuttles Between Lysosomes Endosomes And The Plasma Membrane Colocalizes With Osbpl1a At The Late Endosome
Alternative Antibody Names	Anti-Lysosome-Associated Membrane Glycoprotein 1 antibody Anti-Lamp-1 antibody Anti-Lysosome-Associated Membrane Protein 1 antibody Anti-120 Kda Lysosomal Membrane Glycoprotein antibody Anti-Cd107 Antigen-Like Family Member A antibody Anti-Lgp-120 antibody Anti-Lysosomal Membrane Glycoprotein A antibody Anti-Lgp-A antibody Anti-P2b antibody Anti-Cd Antigen Cd107a antibody Anti-Lamp1 antibody Anti-Lamp-1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CD107a antibody [1D4B] {AF647} (STJA0004271)