Human VTCN1 (V-Set Domain Containing T-Cell Activation Inhibitor 1) Sandwich ELISA Kit (STJE0013068) STJE0013068 上海玉博生物科技有限公司

Human VTCN1 (V-Set Domain Containing T-Cell Activation Inhibitor 1) Sandwich ELISA Kit (STJE0013068)

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产品名称：Human VTCN1 (V-Set Domain Containing T-Cell Activation Inhibitor 1) Sandwich ELISA Kit (STJE0013068)
产品型号：STJE0013068
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human VTCN1 (V-Set Domain Containing T-Cell Activation Inhibitor 1) Sandwich ELISA Kit (STJE0013068)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.054ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This VTCN1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	VTCN1
Gene ID:	79679
Uniprot ID:	VTCN1_HUMAN
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Overexpressed in breast, ovarian, endometrial, renal cell (RCC) and non-small-cell lung cancers (NSCLC). Expressed on activated T- and B-cells, monocytes and dendritic cells, but not expressed in most normal tissues (at protein level). Widely expressed, including in kidney, liver, lung, ovary, placenta, spleen and testis.
Post Translational Modifications	N-glycosylated.
Function	Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Protein Name	V-Set Domain-Containing T-Cell Activation Inhibitor 1 B7 Homolog 4 B7-H4 B7h.5 Immune Costimulatory Protein B7-H4 Protein B7s1 T-Cell Costimulatory Molecule B7x
Database Links
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein Expressed At The Cell Surface A Soluble Form Has Also Been Detected
Alternative ELISA Names	V-Set Domain-Containing T-Cell Activation Inhibitor 1 ELISA kit B7 Homolog 4 ELISA kit B7-H4 ELISA kit B7h.5 ELISA kit Immune Costimulatory Protein B7-H4 ELISA kit Protein B7s1 ELISA kit T-Cell Costimulatory Molecule B7x ELISA kit VTCN1 ELISA kit B7H4 ELISA kit UNQ659 ELISA kit PRO1291 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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