Mouse SLC30A1 (Solute Carrier Family 30, Member 1) Sandwich ELISA Kit Ready-To-Use (STJE0018580) STJE0018580 上海玉博生物科技有限公司

Mouse SLC30A1 (Solute Carrier Family 30, Member 1) Sandwich ELISA Kit Ready-To-Use (STJE0018580)

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产品名称：Mouse SLC30A1 (Solute Carrier Family 30, Member 1) Sandwich ELISA Kit Ready-To-Use (STJE0018580)
产品型号：STJE0018580
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Mouse SLC30A1 (Solute Carrier Family 30, Member 1) Sandwich ELISA Kit Ready-To-Use (STJE0018580)

产品描述

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.054ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This SLC30A1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	Slc30a1
Gene ID:	22782
Uniprot ID:	ZNT1_MOUSE
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Widely expressed.
Post Translational Modifications
Function	Zinc ion:proton antiporter that could function at the plasma membrane mediating zinc efflux from cells against its electrochemical gradient protecting them from intracellular zinc accumulation and toxicity (Probable). Alternatively, could prevent the transport to the plasma membrane of CACNB2, the L-type calcium channels regulatory subunit, through a yet to be defined mechanism. By modulating the expression of these channels at the plasma membrane, could prevent calcium and zinc influx into cells. By the same mechanism, could also prevent L-type calcium channels-mediated heavy metal influx into cells. In some cells, could also function as a zinc ion:proton antiporter mediating zinc entry into the lumen of cytoplasmic vesicles. In macrophages, can increase zinc ions concentration into the lumen of cytoplasmic vesicles containing engulfed bacteria and could help inactivate them.
Protein Name	Proton-Coupled Zinc Antiporter Slc30a1 Solute Carrier Family 30 Member 1 Zinc Transporter 1 Znt-1
Database Links	Reactome: R-MMU-435368
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Basolateral Cell Membrane Cytoplasmic Vesicle Membrane Localization To The Plasma Membrane Is Regulated By Cellular Zinc Status Recruitment To The Plasma Membrane From An Internal Pool Is Stimulated By Zinc While In Absence Of Zinc The Plasma Membrane Pool Is Endocytosed And Degraded Localizes To The Basolateral Surface Of Enterocytes Localizes To Zinc-Containing Intracellular Vesicles In Macrophages
Alternative ELISA Names	Proton-Coupled Zinc Antiporter Slc30a1 ELISA kit Solute Carrier Family 30 Member 1 ELISA kit Zinc Transporter 1 ELISA kit Znt-1 ELISA kit Slc30a1 ELISA kit Znt1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Mouse SLC30A1 (Solute Carrier Family 30, Member 1) Sandwich ELISA Kit Ready-To-Use (STJE0018580)