Anti-ESRP1 antibody (1-220) (STJ116833) STJ116833 上海玉博生物科技有限公司

Anti-ESRP1 antibody (1-220) (STJ116833)

简单介绍

Anti-ESRP1 antibody (1-220) (STJ116833)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ESRP1 (1-220) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ESRP1
Gene ID:	54845
Uniprot ID:	ESRP1_HUMAN
Immunogen Region:	1-220
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ESRP1 (NP_060167.2).
Immunogen Sequence:	MTASPDYLVVLFGITAGATG AKLGSDEKELILLFWKVVDL ANKKVGQLHEVLVRPDQLEL TEDCKEETKIDVESLSSASQ LDQALRQFNQSVSNELNIGV GTSFCLCTDGQLHVRQILHP EASKKNVLLPECFYSFFDLR KEFKKCCPGSPDIDKLDVAT MTEYLNFEKSSSVSRYGASQ VEDMGNIILAMISEPYNHRF SDPERVNYKFESGTCSKMEL

Tissue Specificity	Epithelial cell-specific.
Function	mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. Regulates splicing and expression of genes involved in inner ear development, auditory hair cell differentiation, and cell fate specification in the cochlear epithelium.
Protein Name	Epithelial Splicing Regulatory Protein 1 Rna-Binding Motif Protein 35a Rna-Binding Protein 35a
Database Links	Reactome: R-HSA-6802952 Reactome: R-HSA-6803529
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Epithelial Splicing Regulatory Protein 1 antibody Anti-Rna-Binding Motif Protein 35a antibody Anti-Rna-Binding Protein 35a antibody Anti-ESRP1 antibody Anti-RBM35A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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