Anti-ETS1 antibody (11-60 aa) (STJ93009) STJ93009 上海玉博生物科技有限公司

Anti-ETS1 antibody (11-60 aa) (STJ93009)

简单介绍

Anti-ETS1 antibody (11-60 aa) (STJ93009)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Protein C-ets-1 (11-60 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:5000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ETS1
Gene ID:	2113
Uniprot ID:	ETS1_HUMAN
Immunogen Region:	11-60 aa
Specificity:	ETS1 Polyclonal Antibody detects endogenous levels of ETS1 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human ETS1 at the amino acid range 11-60

Post Translational Modifications	Sumoylated on Lys-15 and Lys-227, preferentially with SUMO2.which inhibits transcriptional activity. Ubiquitinated.which induces proteasomal degradation. Phosphorylation at Ser-251, Ser-282 and Ser-285 by CaMK2/CaMKII in response to calcium signaling decreases affinity for DNA: an increasing number of phosphoserines causes DNA-binding to become progressively weaker.
Function	Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion. Isoform Ets-1 p27: Acts as a dominant-negative for isoform c-ETS-1A.
Protein Name	Protein C-Ets-1 P54
Database Links	Reactome: R-HSA-2559585
Cellular Localisation	Nucleus Cytoplasm Delocalizes From Nucleus To Cytoplasm When Coexpressed With Isoform Ets-1 P27
Alternative Antibody Names	Anti-Protein C-Ets-1 antibody Anti-P54 antibody Anti-ETS1 antibody Anti-EWSR2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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