Anti-ETS1 antibody [10D2] (STJ98058) STJ98058 上海玉博生物科技有限公司

Anti-ETS1 antibody [10D2] (STJ98058)

简单介绍

Anti-ETS1 antibody [10D2] (STJ98058)

产品描述

Host:	Mouse
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Mouse monoclonal antibody anti-Protein C-ets-1 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Monoclonal
Clone ID:	10D2
Conjugation:	Unconjugated
Isotype:	IgG1
Formulation:	Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC 1:200-1:1000 ELISA 1:10000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ETS1
Gene ID:	2113
Uniprot ID:	ETS1_HUMAN
Specificity:	ETS1 Monoclonal Antibody detects endogenous levels of ETS1 protein.
Immunogen:	Purified recombinant fragment of human ETS1 expressed in E. Coli.

Post Translational Modifications	Sumoylated on Lys-15 and Lys-227, preferentially with SUMO2.which inhibits transcriptional activity. Ubiquitinated.which induces proteasomal degradation. Phosphorylation at Ser-251, Ser-282 and Ser-285 by CaMK2/CaMKII in response to calcium signaling decreases affinity for DNA: an increasing number of phosphoserines causes DNA-binding to become progressively weaker.
Function	Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion. Isoform Ets-1 p27: Acts as a dominant-negative for isoform c-ETS-1A.
Protein Name	Protein C-Ets-1 P54
Database Links	Reactome: R-HSA-2559585
Cellular Localisation	Nucleus Cytoplasm Delocalizes From Nucleus To Cytoplasm When Coexpressed With Isoform Ets-1 P27
Alternative Antibody Names	Anti-Protein C-Ets-1 antibody Anti-P54 antibody Anti-ETS1 antibody Anti-EWSR2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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