Anti-ETV4 antibody (50-109 aa) [1A2G3] (STJ98316) STJ98316 上海玉博生物科技有限公司

Anti-ETV4 antibody (50-109 aa) [1A2G3] (STJ98316)

简单介绍

Anti-ETV4 antibody (50-109 aa) [1A2G3] (STJ98316)

产品描述

Host:	Mouse
Applications:	WB/ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Mouse monoclonal antibody anti-ETS translocation variant 4 (50-109 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Monoclonal
Clone ID:	1A2G3
Conjugation:	Unconjugated
Isotype:	IgG1
Formulation:	Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 ELISA 1:10000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ETV4
Gene ID:	2118
Uniprot ID:	ETV4_HUMAN
Immunogen Region:	50-109 aa
Specificity:	PEA3 Monoclonal Antibody detects endogenous levels of PEA3 protein.
Immunogen:	Purified recombinant fragment of human PEA3 (aa50-109) expressed in E. Coli.

Post Translational Modifications	Sumoylated.enhanced upon ERK/MAP kinase pathway activation, it positively regulates the transcriptional activator capacity. Sumoylation at Lys-96 probably requires phosphorylation at Ser-101. Transiently polysumoylated and desumoylated by SENP1. Sumoylation is a prerequisite to polyubiquitination which in turn increases proteasomal-mediated degradation. Probably polyubiquitinated by RNF4 and deubiquitinated by USP2.
Function	Transcriptional activator. May play a role in keratinocyte differentiation. (Microbial infection) Binds to the enhancer of the adenovirus E1A gene and acts as a transcriptional activator.the core-binding sequence is 5'-ACGGAATGT-3'.
Protein Name	Ets Translocation Variant 4 Adenovirus E1a Enhancer-Binding Protein E1a-F Polyomavirus Enhancer Activator 3 Homolog Protein Pea3
Database Links	Reactome: R-HSA-5687128
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Ets Translocation Variant 4 antibody Anti-Adenovirus E1a Enhancer-Binding Protein antibody Anti-E1a-F antibody Anti-Polyomavirus Enhancer Activator 3 Homolog antibody Anti-Protein Pea3 antibody Anti-ETV4 antibody Anti-E1AF antibody Anti-PEA3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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