Anti-ETV4 antibody (79-178) (STJ115799) STJ115799 上海玉博生物科技有限公司

Anti-ETV4 antibody (79-178) (STJ115799)

简单介绍

Anti-ETV4 antibody (79-178) (STJ115799)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ETV4 (79-178) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ETV4
Gene ID:	2118
Uniprot ID:	ETV4_HUMAN
Immunogen Region:	79-178
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 79-178 of human ETV4 (NP_001977.1).
Immunogen Sequence:	PDFHSENLAFHSPTTRIKKE PQSPRTDPALSCSRKPPLPY HHGEQCLYSSAYDPPRQIAI KSPAPGALGQSPLQPFPRAE QRNFLRSSGTSQPHPGHGYL

Tissue Specificity	Expressed in keratinocytes.
Post Translational Modifications	Sumoylated.enhanced upon ERK/MAP kinase pathway activation, it positively regulates the transcriptional activator capacity. Sumoylation at Lys-96 probably requires phosphorylation at Ser-101. Transiently polysumoylated and desumoylated by SENP1. Sumoylation is a prerequisite to polyubiquitination which in turn increases proteasomal-mediated degradation. Probably polyubiquitinated by RNF4 and deubiquitinated by USP2.
Function	Transcriptional activator. May play a role in keratinocyte differentiation. (Microbial infection) Binds to the enhancer of the adenovirus E1A gene and acts as a transcriptional activator.the core-binding sequence is 5'-ACGGAATGT-3'.
Protein Name	Ets Translocation Variant 4 Adenovirus E1a Enhancer-Binding Protein E1a-F Polyomavirus Enhancer Activator 3 Homolog Protein Pea3
Database Links	Reactome: R-HSA-5687128
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Ets Translocation Variant 4 antibody Anti-Adenovirus E1a Enhancer-Binding Protein antibody Anti-E1a-F antibody Anti-Polyomavirus Enhancer Activator 3 Homolog antibody Anti-Protein Pea3 antibody Anti-ETV4 antibody Anti-E1AF antibody Anti-PEA3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

产品目录