Anti-ETV6 antibody (1-300) (STJ118114) STJ118114 上海玉博生物科技有限公司

Anti-ETV6 antibody (1-300) (STJ118114)

简单介绍

Anti-ETV6 antibody (1-300) (STJ118114)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ETV6 (1-300) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ETV6
Gene ID:	2120
Uniprot ID:	ETV6_HUMAN
Immunogen Region:	1-300
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ETV6 (NP_001978.1).
Immunogen Sequence:	MSETPAQCSIKQERISYTPP ESPVPSYASSTPLHVPVPRA LRMEEDSIRLPAHLRLQPIY WSRDDVAQWLKWAENEFSLR PIDSNTFEMNGKALLLLTKE DFRYRSPHSGDVLYELLQHI LKQRKPRILFSPFFHPGNSI HTQPEVILHQNHEEDNCVQR TPRPSVDNVHHNPPTIELLH RSRSPITTNHRPSPDPEQRP LRSPLDNMIRRLSPAERAQG PRPHQENNHQESYPLSVSP

Tissue Specificity	Ubiquitous.
Post Translational Modifications	Phosphorylation of Ser-257 by MAPK14 (p38) inhibits ETV6 transcriptional repression.
Function	Transcriptional repressor.binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation.
Protein Name	Transcription Factor Etv6 Ets Translocation Variant 6 Ets-Related Protein Tel1 Tel
Database Links	Reactome: R-HSA-9673768 Reactome: R-HSA-9703465
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Transcription Factor Etv6 antibody Anti-Ets Translocation Variant 6 antibody Anti-Ets-Related Protein Tel1 antibody Anti-Tel antibody Anti-ETV6 antibody Anti-TEL antibody Anti-TEL1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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