Mouse STX1A (Syntaxin 1A, Brain) Sandwich ELISA Kit Ready-To-Use (STJE0018776) STJE0018776 上海玉博生物科技有限公司

Mouse STX1A (Syntaxin 1A, Brain) Sandwich ELISA Kit Ready-To-Use (STJE0018776)

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产品名称：Mouse STX1A (Syntaxin 1A, Brain) Sandwich ELISA Kit Ready-To-Use (STJE0018776)
产品型号：STJE0018776
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Mouse STX1A (Syntaxin 1A, Brain) Sandwich ELISA Kit Ready-To-Use (STJE0018776)

产品描述

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.057ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This STX1A Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	Stx1a
Gene ID:	20907
Uniprot ID:	STX1A_MOUSE
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Expressed in the striatum (at protein level). Expressed in the ileum.
Post Translational Modifications	Phosphorylated by CK2. Phosphorylation at Ser-188 by DAPK1 significantly decreases its interaction with STXBP1. Phosphorylated by CK2. Phosphorylation at Ser-188 by DAPK1 significantly decreases its interaction with STXBP1. Sumoylated, sumoylation is required for regulation of synaptic vesicle endocytosis.
Function	Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final fusion. Participates in the calcium-dependent regulation of acrosomal exocytosis in sperm. Also plays an important role in the exocytosis of hormones such as insulin or glucagon-like peptide 1 (GLP-1).
Protein Name	Syntaxin-1a Neuron-Specific Antigen Hpc-1
Database Links	Reactome: R-MMU-181429 Reactome: -MMU-181430 Reactome: -MMU-210500 Reactome: -MMU-212676 Reactome: -MMU-264642 Reactome: -MMU-449836 Reactome: -MMU-5682910 Reactome: -MMU-888590 Reactome: -MMU-9609523
Cellular Localisation	Cytoplasmic Vesicle Secretory Vesicle Synaptic Vesicle Membrane Single-Pass Type Iv Membrane Protein Synapse Synaptosome Cell Membrane Colocalizes With Kcnb1 At The Cell Membrane
Alternative ELISA Names	Syntaxin-1a ELISA kit Neuron-Specific Antigen Hpc-1 ELISA kit Stx1a ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Mouse STX1A (Syntaxin 1A, Brain) Sandwich ELISA Kit Ready-To-Use (STJE0018776)