Anti-EVC antibody (743-992) (STJ114509) STJ114509 上海玉博生物科技有限公司

Anti-EVC antibody (743-992) (STJ114509)

简单介绍

Anti-EVC antibody (743-992) (STJ114509)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-EVC (743-992) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:1000-1:3000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	EVC
Gene ID:	2121
Uniprot ID:	EVC_HUMAN
Immunogen Region:	743-992
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 743-992 of human EVC (NP_714928.1).
Immunogen Sequence:	AIGQALLVHARNAATKSRAK DRDDFKRTLMEAAVESVYVT SAGVSRLVQAYYQQIGRIME DHEERKLQHLKTLQGERMEN YKLRKKQELSNPSSGSRTAG GAHETSQAVHQRMLSQQKRF LAQFPVHQQMRLHAQQQQAG VMDLLEAQLETQLQEAEQNF ISELAALARVPLAESKLLPA KRGLLEKPLRTKRKKPLPQE RGDLGVPNNEDLASGDQTSG SLSSKRLSQQESEAGDSGN

Tissue Specificity	Found in the developing vertebral bodies, ribs, upper and lower limbs, heart, kidney, lung.
Function	Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Involved in endochondral growth and skeletal development.
Protein Name	Evc Complex Member Evc Dwf-1 Ellis-Van Creveld Syndrome Protein
Database Links	Reactome: R-HSA-5632684 Reactome: R-HSA-5635838
Cellular Localisation	Cell Membrane Single-Pass Membrane Protein Cytoplasm Cytoskeleton Cilium Basal Body Cell Projection Cilium Cilium Membrane Evc2 Is Required For The Localization Of Evc At The Base Of Primary Cilia The Evc Complex Localizes At The Base Of Cilia In The Evc Zone Of Primary Cilia In A Efcab7-Dependent Manner
Alternative Antibody Names	Anti-Evc Complex Member Evc antibody Anti-Dwf-1 antibody Anti-Ellis-Van Creveld Syndrome Protein antibody Anti-EVC antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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