Anti-EXOC1 antibody (645-894) (STJ116329) STJ116329 上海玉博生物科技有限公司

Anti-EXOC1 antibody (645-894) (STJ116329)

简单介绍

Anti-EXOC1 antibody (645-894) (STJ116329)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-EXOC1 (645-894) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	EXOC1
Gene ID:	55763
Uniprot ID:	EXOC1_HUMAN
Immunogen Region:	645-894
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 645-894 of human EXOC1 (NP_001020095.1).
Immunogen Sequence:	RNFDKCISNQIRQMEEVKIS KKSKVGILPFVAEFEEFAGL AESIFKNAERRGDLDKAYTK LIRGVFVNVEKVANESQKTP RDVVMMENFHHIFATLSRLK ISCLEAEKKEAKQKYTDHLQ SYVIYSLGQPLEKLNHFFEG VEARVAQGIREEEVSYQLAF NKQELRKVIKEYPGKEVKKG LDNLYKKVDKHLCEEENLLQ VVWHSMQDEFIRQYKHFEGL IARCYPGSGVTMEFTIQDI

Function	Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (Microbial infection) Has an antiviral effect against flaviviruses by affecting viral RNA transcription and translation through the sequestration of elongation factor 1-alpha (EEF1A1). This results in decreased viral RNA synthesis and decreased viral protein translation.
Protein Name	Exocyst Complex Component 1 Exocyst Complex Component Sec3
Database Links	Reactome: R-HSA-1445148 Reactome: R-HSA-264876 Reactome: R-HSA-5620916
Cellular Localisation	Midbody Midbody Ring Cytoplasm Perinuclear Region Cell Membrane Colocalizes With Cntrl/Centriolin At The Midbody Ring Localizes In Cell Membrane In The Presence Of Slc6a9
Alternative Antibody Names	Anti-Exocyst Complex Component 1 antibody Anti-Exocyst Complex Component Sec3 antibody Anti-EXOC1 antibody Anti-SEC3 antibody Anti-SEC3L1 antibody Anti-BM-012 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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