Anti-FAAH antibody (480-579) [S6MR] (STJ11101996) STJ11101996 上海玉博生物科技有限公司

Anti-FAAH antibody (480-579) [S6MR] (STJ11101996)

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产品名称：Anti-FAAH antibody (480-579) [S6MR] (STJ11101996)
产品型号：STJ11101996
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-FAAH antibody (480-579) [S6MR] (STJ11101996)

产品描述

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-FAAH1 (480-579) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Monoclonal
Clone ID:	S6MR
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FAAH
Gene ID:	2166
Uniprot ID:	FAAH1_HUMAN
Immunogen Region:	480-579
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 480-579 of human FAAH1 (O00519).
Immunogen Sequence:	DLNAPGRATGAVSYTMLYNC LDFPAGVVPVTTVTAEDEAQ MEHYRGYFGDIWDKMLQKGM KKSVGLPVAVQCVALPWQEE LCLRFMREVERLMTPEKQSS

Tissue Specificity	Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate.
Function	Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates. It can also catalyze the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol). FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets of intracellular, but not of extracellular, N-fatty acyl amino acids.
Protein Name	Fatty-Acid Amide Hydrolase 1 Anandamide Amidohydrolase 1 Fatty Acid Ester Hydrolase Oleamide Hydrolase 1
Database Links	Reactome: R-HSA-2142753
Cellular Localisation	Endomembrane System Single-Pass Membrane Protein Cytoplasm Cytoskeleton Seems To Be Attached To Intracellular Membranes And A Portion Of The Cytoskeletal Network
Alternative Antibody Names	Anti-Fatty-Acid Amide Hydrolase 1 antibody Anti-Anandamide Amidohydrolase 1 antibody Anti-Fatty Acid Ester Hydrolase antibody Anti-Oleamide Hydrolase 1 antibody Anti-FAAH antibody Anti-FAAH1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-FAAH antibody (480-579) [S6MR] (STJ11101996)