Mouse TP63 (Tumor Protein P63) Sandwich ELISA Kit Ready-To-Use (STJE0019134) STJE0019134 上海玉博生物科技有限公司

Mouse TP63 (Tumor Protein P63) Sandwich ELISA Kit Ready-To-Use (STJE0019134)

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产品名称：Mouse TP63 (Tumor Protein P63) Sandwich ELISA Kit Ready-To-Use (STJE0019134)
产品型号：STJE0019134
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Mouse TP63 (Tumor Protein P63) Sandwich ELISA Kit Ready-To-Use (STJE0019134)

产品描述

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.054ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This TP63 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	Tp63
Gene ID:	22061
Uniprot ID:	P63_MOUSE
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Widely expressed, notably in thymus, prostate, placenta and skeletal muscle, although the precise isoform varies according to tissue type. Progenitor cell layers of skin, breast and prostate express high levels of DeltaN-type isoforms.
Post Translational Modifications	May be sumoylated. Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein.
Function	Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Activates transcription of the p21 promoter. Activates RIPK4 transcription. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge.
Protein Name	Tumor Protein 63 P63 Transformation-Related Protein 63 Tp63 Tumor Protein P73-Like P73l
Database Links	Reactome: R-MMU-6804759
Cellular Localisation	Nucleus
Alternative ELISA Names	Tumor Protein 63 ELISA kit P63 ELISA kit Transformation-Related Protein 63 ELISA kit Tp63 ELISA kit Tumor Protein P73-Like ELISA kit P73l ELISA kit Tp63 ELISA kit P63 ELISA kit P73l ELISA kit Tp73l ELISA kit Trp63 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Mouse TP63 (Tumor Protein P63) Sandwich ELISA Kit Ready-To-Use (STJE0019134)