Anti-CDCA2 antibody (724-1023) (STJ113630) STJ113630 上海玉博生物科技有限公司

Anti-CDCA2 antibody (724-1023) (STJ113630)

简单介绍

Anti-CDCA2 antibody (724-1023) (STJ113630)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CDCA2 (724-1023) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CDCA2
Gene ID:	157313
Uniprot ID:	CDCA2_HUMAN
Immunogen Region:	724-1023
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 724-1023 of human CDCA2 (NP_689775.2).
Immunogen Sequence:	SDSPKPALTLQQGQEFSAGG QNAENLCQFFKISPDLNIKC ERKDDFLGAAEGKLQCNRLM PNSQKDCHCLGDVLIENTKE SKSQSEDLGRKPMESSSVVS CRDRKDRRRSMCYSDGRSLH LEKNGNHTPSSSVGSSVEIS LENSELFKDLSDAIEQTFQR RNSETKVRRSTRLQKDLENE GLVWISLPLPSTSQKAKRRT ICTFDSSGFESMSPIKETVS SRQKPQMAPPVSDPENSQG

Tissue Specificity	Ubiquitously expressed.
Post Translational Modifications	Phosphorylated by CDK1. May regulate its subcellular location.
Function	Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.
Protein Name	Cell Division Cycle-Associated Protein 2 Recruits Pp1 Onto Mitotic Chromatin At Anaphase Protein Repo-Man
Cellular Localisation	Nucleus Excluded From The Nucleolus Present In Nucleoplasm Throughout The G1 S And G2 Stages Of The Cell Cycle During M Phase It Becomes Diffuse Throughout The Cell As The Nuclear Membrane Breaks Down And Faintly Accumulates Later On Metaphase Chromatin As The Cell Progresses To Anaphase It Accumulates On Chromatin
Alternative Antibody Names	Anti-Cell Division Cycle-Associated Protein 2 antibody Anti-Recruits Pp1 Onto Mitotic Chromatin At Anaphase Protein antibody Anti-Repo-Man antibody Anti-CDCA2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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