Anti-FCGR3B antibody (1-233) (STJ110203) STJ110203 上海玉博生物科技有限公司

Anti-FCGR3B antibody (1-233) (STJ110203)

简单介绍

Anti-FCGR3B antibody (1-233) (STJ110203)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-FCGR3B (1-233) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FCGR3B
Gene ID:	2215
Uniprot ID:	FCG3B_HUMAN
Immunogen Region:	1-233
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FCGR3B (NP_000561.3).
Immunogen Sequence:	MWQLLLPTALLLLVSAGMRT EDLPKAVVFLEPQWYSVLEK DSVTLKCQGAYSPEDNSTQW FHNENLISSQASSYFIDAAT VNDSGEYRCQTNLSTLSDPV QLEVHIGWLLLQAPRWVFKE EDPIHLRCHSWKNTALHKVT YLQNGKDRKYFHHNSDFHIP KATLKDSGSYFCRGLVGSKN VSSETVNITITQGLAVSTIS SFSPPGYQVSFCLVMVLLFA VDTGLYFSVKTNI

Tissue Specificity	Expressed specifically by polymorphonuclear leukocytes (neutrophils). Also expressed by stimulated eosinophils.
Post Translational Modifications	Glycosylated. Glycosylation plays an inhibitory role in the interaction with IgG3. The soluble form is produced by a proteolytic cleavage.
Function	Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Protein Name	Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B Fc-Gamma Riii-Beta Cd16-I Fc-Gamma Riii Fc-Gamma Riiib Fcriii Fcriiib Fcr-10 Igg Fc Receptor Iii-1 Cd Antigen Cd16b
Database Links	Reactome: R-HSA-163125 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor Secreted Secreted After Cleavage
Alternative Antibody Names	Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B antibody Anti-Fc-Gamma Riii-Beta antibody Anti-Cd16-I antibody Anti-Fc-Gamma Riii antibody Anti-Fc-Gamma Riiib antibody Anti-Fcriii antibody Anti-Fcriiib antibody Anti-Fcr-10 antibody Anti-Igg Fc Receptor Iii-1 antibody Anti-Cd Antigen Cd16b antibody Anti-FCGR3B antibody Anti-CD16B antibody Anti-FCG3 antibody Anti-FCGR3 antibody Anti-IGFR3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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