Anti-CDH23/USH1D antibody (Internal) (STJ71691) STJ71691-100 上海玉博生物科技有限公司

Anti-CDH23/USH1D antibody (Internal) (STJ71691)

简单介绍

Anti-CDH23/USH1D antibody (Internal) (STJ71691)

产品描述

Host:	Goat
Applications:	Pep-ELISA/WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-CDH23/USH1D (Internal) is suitable for use in ELISA and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-1-3µg/ml ELISA-antibody detection limit dilution 1:1000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	CDH23
Gene ID:	64072
Uniprot ID:	CAD23_HUMAN
Immunogen Region:	Internal
Accession Number:	NP_071407.3; NP_443068.1
Specificity:	This antibody is expected to recognize both reported isoforms (NP_071407.3; NP_443068.1).
Immunogen Sequence:	YNISLYENVTVGTS

Function	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
Protein Name	Cadherin-23 Otocadherin
Database Links	Reactome: R-HSA-9662360 Reactome: R-HSA-9662361
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-Cadherin-23 antibody Anti-Otocadherin antibody Anti-CDH23 antibody Anti-KIAA1774 antibody Anti-KIAA1812 antibody Anti-UNQ1894 antibody Anti-PRO4340 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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